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View complete bundle Grant ProgramUSA FederalStatus: Open
NIH SBIR/STTR Biotech Grants
Official funding support offered by the National Institutes of Health (NIH). Offset costs with up to Phase I: $150K-$275K | Phase II: $1M-$1.8M.
Research review: AshwaniVerified
FSI Digital Funding Research • Reviewed June 9, 2026How does a business qualify for the NIH SBIR?
To qualify for the NIH SBIR/STTR Biotech Grants, a business must be incorporated in the United States and demonstrate active operations. The program offers up to Phase I: $150K-$275K | Phase II: $1M-$1.8M in non-dilutive capital, which is categorized under a Competitive funding difficulty level. Applicants must ensure they meet all technical benchmarks and file using official channels before specific application windows close.
Typical Applicant Profile: Health, Life Sciences, & MedTech Grants
Est. Funding$150,000 – $1.8M
Avg Revenue$150k – $12M
Min. Team Size2 – 40+ researchers
Target StageClinical Trials & R&D
Key Qualifiers
- •Medical device, digital health, or drug discovery projects
- •Academic partnerships or patent-pending technologies
- •Investigator-initiated clinical trial plans
Rejection Risk Factors
- •Generic wellness apps or fitness coaching platforms
- •No regulatory compliance pathway (FDA/Health Canada)
- •Lack of clinical validation advisory board
How Does Your Business Compare?
Life science funding (NIH/CIHR) requires strong clinical proof-of-concept and a clear regulatory pathway to survive panel reviews. Estimate your Funding Match Score (e.g. 82/100) based on your team, location, and development activities.
Program Status & Update Log
- •Updated January 2026: Phase I funding amounts adjusted to $275,000 for biomedical technology developers.
Known as America's Seed Fund for life sciences, these awards fund early-stage research and development with commercialization potential in biotech, medical devices, and digital health.
Key Features
| Funding Limit | Phase I: $150K-$275K | Phase II: $1M-$1.8M |
| Program Agency | National Institutes of Health (NIH) |
| Funding Type | Grant |
| Jurisdiction | USA Federal |
Deadlines & Difficulty
| Difficulty | Competitive Match |
| Deadline Status | Multiple Windows |
| Official Portal | Visit Official Site |
💡 Expert Insider Tips
- •Biotech startups should partner with a university or research hospital (required for STTR) to increase credibility and run validation clinical trials cheaply.
Target Industries
View custom eligibility criteria and stacking rules for your industry:
Related Resources & Guides
Federal Grant Application Strategies
Core guidelines for submitting technical proposals to government agencies.
Illustrative Stacking Models & Case Studies
Examine how typical companies combine wage support, research funds, and local credits.
Regional Directories & Industry Guides
Determine Your Funding Match Probability
Our pre-qualification review analyzes program requirements, stacking possibilities, and alignment to minimize filing rejections.
Comparison Guides
Compare NIH SBIR/STTR Biotech Grants against other active programs:
Local Business Guides
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Official Program Alignment
FSI Digital reviews eligibility standards in accordance with official guidelines. We never guarantee funding; all approvals are subject to official government program review.
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