NIH SBIR/STTR Biotech Grants
Official funding support offered by the National Institutes of Health (NIH). Offset costs with up to Phase I: $150K-$275K | Phase II: $1M-$1.8M.

How does a business qualify for the NIH SBIR?
To qualify for the NIH SBIR/STTR Biotech Grants, a business must be incorporated in the United States and demonstrate active operations. The program offers up to Phase I: $150K-$275K | Phase II: $1M-$1.8M in non-dilutive capital, which is categorized under a Competitive funding difficulty level. Applicants must ensure they meet all technical benchmarks and file using official channels before specific application windows close.
Known as America's Seed Fund for life sciences, these awards fund early-stage research and development with commercialization potential in biotech, medical devices, and digital health.
Key Features
| Funding Limit | Phase I: $150K-$275K | Phase II: $1M-$1.8M |
| Program Agency | National Institutes of Health (NIH) |
| Funding Type | Grant |
| Jurisdiction | USA Federal |
Deadlines & Difficulty
| Difficulty | Competitive Match |
| Deadline Status | Multiple Windows |
| Official Portal | Visit Official Site |
π‘ Expert Insider Tips
- β’Biotech startups should partner with a university or research hospital (required for STTR) to increase credibility and run validation clinical trials cheaply.
Related Resources & Guides
SBIR Deep-Tech Grant Application Guide
Navigate Phase I and Phase II technical risk writing models.
USA Federal Grants Application Steps
How to set up SAM.gov entity details and submit clean applications.
Determine Your Funding Match Probability
Our pre-qualification review analyzes program requirements, stacking possibilities, and alignment to minimize filing rejections.
Funding Eligibility Estimator
Calculate potential matching grants and tax credits for your business profile.
Official Program Alignment
FSI Digital reviews eligibility standards in accordance with official guidelines. We never guarantee funding; all approvals are subject to official government program review.
