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HomeGrant DatabaseNIH SBIR/STTR Biotech Grants
Grant ProgramUSA Federal

NIH SBIR/STTR Biotech Grants

Official funding support offered by the National Institutes of Health (NIH). Offset costs with up to Phase I: $150K-$275K | Phase II: $1M-$1.8M.

Reviewed by Ashwani
Research review: AshwaniVerified
FSI Digital Funding Research β€’ Reviewed June 9, 2026

How does a business qualify for the NIH SBIR?

To qualify for the NIH SBIR/STTR Biotech Grants, a business must be incorporated in the United States and demonstrate active operations. The program offers up to Phase I: $150K-$275K | Phase II: $1M-$1.8M in non-dilutive capital, which is categorized under a Competitive funding difficulty level. Applicants must ensure they meet all technical benchmarks and file using official channels before specific application windows close.

Known as America's Seed Fund for life sciences, these awards fund early-stage research and development with commercialization potential in biotech, medical devices, and digital health.

Key Features

Funding LimitPhase I: $150K-$275K | Phase II: $1M-$1.8M
Program AgencyNational Institutes of Health (NIH)
Funding TypeGrant
JurisdictionUSA Federal

Deadlines & Difficulty

DifficultyCompetitive Match
Deadline StatusMultiple Windows
Official PortalVisit Official Site

πŸ’‘ Expert Insider Tips

  • β€’Biotech startups should partner with a university or research hospital (required for STTR) to increase credibility and run validation clinical trials cheaply.

Related Resources & Guides

SBIR Deep-Tech Grant Application Guide

Navigate Phase I and Phase II technical risk writing models.

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Last reviewed: June 2026

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